Human AGR3 HEK293 Overexpression Lysate MBS8115269 from MyBioSource.com

Description

Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been characterised as a novel potential biomarker both for breast cancer prognosis and early breast cancer detection from blood.

This Human AGR3 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of AGR3 protein from the overexpression lysate was verified

Product Specs
ItemHuman AGR3 HEK293 Overexpression Lysate
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS8115269
Format1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF
ApplicationsWestern Blot (WB)
Quantity0.3 mg
Molecular Weight19,171 Da
NCBI Full Gene Nameanterior gradient 3, protein disulphide isomerase family member
NCBI Gene AliaseshAG-3, BCMP11, HAG3, AG-3, AG3, PDIA18
Molecule NameAGR3
TypeOverexpression Lysate
Domain/Region/TerminusMet1-Leu166
Source/Expression SystemHEK293 Cells
Cell LineHEK293